In vitro and in vivo evaluations of a hydrophilic 64Cu-bis(thiosemicarbazonato)-glucose conjugate for hypoxia imaging.

UNLABELLED: A water-soluble glucose conjugate of the hypoxia tracer 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) (64Cu-ATSM) was synthesized and radiolabeled (64Cu-ATSE/A-G). Here we report our initial biological experiments with 64Cu-ATSE/A-G and compare the results with those obtained for 64Cu-AT...

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Bibliographic Details
Main Authors: Bayly, SR, King, R, Honess, D, Barnard, P, Betts, H, Holland, J, Hueting, R, Bonnitcha, P, Dilworth, JR, Aigbirhio, F, Christlieb, M
Format: Journal article
Language:English
Published: 2008