Measuring vaccine efficacy against infection and disease in clinical trials: sources and magnitude of bias in COVID-19 vaccine efficacy estimates

<p><strong>Background</strong></p> Phase III trials have estimated COVID-19 vaccine efficacy (VE) against symptomatic and asymptomatic infection. We explore the direction and magnitude of potential biases in these estimates and their implications for vaccine protection agains...

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Bibliographic Details
Main Authors: Williams, LR, Ferguson, NM, Donnelly, CA, Grassly, NC
Format: Journal article
Language:English
Published: Oxford University Press 2021