Enantiospecific alkylations of alanine
Reaction of ferrocenecarbaldehyde 3 with sodium (S)-alaninate followed by pivaloyl chloride generates (2S,4S)-2-ferrocenyl-3-pivaloyl-4-methyl-1,3-oxazolidin-5-one 5 (>98% de). Compound 5 undergoes stereospecific 4-alkylation with complete retention of configuration on treatment sequentially...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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