Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain

Neurological complications, including encephalopathy and stroke, occur in a significant proportion of COVID-19 cases but viral protein is seldom detected in the brain parenchyma. To model this situation, we developed a novel low-inoculum K18-hACE2 mouse model of SARS-CoV-2 infection during which act...

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Bibliographic Details
Main Authors:	Dunai, C, Hetherington, C, Boardman, SA, Clark, JJ, Sharma, P, Subramaniam, K, Tharmaratnam, K, Needham, EJ, Williams, R, Huang, Y, Wood, GK, Collie, C, Fower, A, Fox, H, Ellul, MA, Held, M, Egbe, FN, Griffiths, M, Solomon, T, Breen, G, Kipar, A, Cavanagh, J, Irani, SR, Vincent, A
Format:	Journal article
Language:	English
Published:	Frontiers Media 2024

Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain

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