Application of a challenge model to assess the protective efficacy of oral typhoid vaccines in humans

Application of a challenge model to assess the protective efficacy of oral typhoid vaccines in humans

<p>Human infection by Salmonella Typhi has been occurring for the last 50,000 years and still accounts for &Tilde; 22million new cases each year worldwide. Through faeco-oral transmission, this human-restricted infection disproportionately affects the most impoverished sections of ende...

Полное описание

Библиографические подробности
Главные авторы:	Darton, T, Pollard, A, Angus, B
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Vaccines

Схожие документы

Typhoid epidemiology, diagnostics and the human challenge model.
по: Darton, T, и др.
Опубликовано: (2014)

Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever
по: Christoph J. Blohmke, и др.
Опубликовано: (2017-10-01)

Advancing the management and control of typhoid fever: A review of the historical role of human challenge studies
по: Waddington, C, и др.
Опубликовано: (2014)

Molecular correlates of vaccine-induced protection against typhoid fever
по: Henderson Zhu, и др.
Опубликовано: (2023-08-01)

Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies.
по: Waddington, C, и др.
Опубликовано: (2014)

Typhoid vaccines. Historical aspects of typhoid vaccine development, and currently available products
по: M. V. Abramtseva, и др.
Опубликовано: (2021-07-01)

Why the development of effective typhoid control measures requires the use of human challenge studies.
по: Jones, C, и др.
Опубликовано: (2014)

A <i>Salmonella</i> Typhi Controlled Human Infection Study for Assessing Correlation between Bactericidal Antibodies and Protection against Infection Induced by Typhoid Vaccination
по: Elizabeth Jones, и др.
Опубликовано: (2021-06-01)

Assessment of vaccine herd protection in a cluster-randomised trial of Vi conjugate vaccine against typhoid fever: results of further analysisResearch in context
по: Farhana Khanam, и др.
Опубликовано: (2023-04-01)

Why the development of effective typhoid control measures requires the use of human challenge studies
по: Claire eJones, и др.
Опубликовано: (2014-12-01)

Opinion of Parents Regarding Conjugate Typhoid Vaccine
по: M.Hanif Memon, и др.
Опубликовано: (2020-12-01)

Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model
по: Fresnay, S, и др.
Опубликовано: (2017)

A forecast of typhoid conjugate vaccine introduction and demand in typhoid endemic low- and middle-income countries to support vaccine introduction policy and decisions
по: Vittal Mogasale, и др.
Опубликовано: (2017-09-01)

Typhoid vaccine landscape
по: Pollard, A
Опубликовано: (2012)

Costs of typhoid vaccination for international travelers from the United States
по: Heesoo Joo, и др.
Опубликовано: (2025-03-01)

Oral challenge with wild-type Salmonella Typhi induces distinct changes in B cell subsets in individuals who develop typhoid disease.
по: Toapanta, F, и др.
Опубликовано: (2016)

Oral wild-type Salmonella Typhi challenge induces activation of circulating monocytes and dendritic cells in individuals who develop typhoid disease
по: Toapanta, F, и др.
Опубликовано: (2015)

Using a human challenge model of infection to measure vaccine efficacy: a randomised, controlled trial comparing the typhoid vaccines M01ZH09 with placebo and Ty21a
по: Darton, T, и др.
Опубликовано: (2016)

Oral Cholera Vaccine Efficacy and Effectiveness
по: Katerina Rok Song, и др.
Опубликовано: (2021-12-01)

Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans
по: Fresnay, S, и др.
Опубликовано: (2016)

Public engagement during a typhoid conjugate vaccine trial in Lalitpur, Nepal- experience, challenges and lessons learnt
по: Ashata Dahal, и др.
Опубликовано: (2022-11-01)

Typhoid vaccine: A case for inclusion in national program
по: Pragya Sharma, и др.
Опубликовано: (2011-01-01)

Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever
по: Deborah L. Cross, и др.
Опубликовано: (2020-12-01)

Typhoid conjugate vaccines: a step towards typhoid control
по: Shakya, M, и др.
Опубликовано: (2024)

Demonstration of primary and asymptomatic DNAaemia in participants challenged with Salmonella Typhi (Quailes strain) during the development of a human model of typhoid infection
по: Darton, T, и др.
Опубликовано: (2012)

Human challenge study with a Shigella bioconjugate vaccine: Analyses of clinical efficacy and correlate of protection
по: Kawsar R. Talaat, и др.
Опубликовано: (2021-04-01)

Typhoid in Pakistan: Challenges, Efforts, and Recommendations
по: Tharwani ZH, и др.
Опубликовано: (2022-05-01)

Malawi vaccination drive: An integrated immunization campaign against typhoid, measles, rubella, and polio; health benefits and potential challenges
по: Adriano Focus Lubanga, и др.
Опубликовано: (2023-08-01)

The Typhoid Vaccine Acceleration Consortium (TyVAC): vaccine effectiveness study designs: accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK
по: Meiring, J, и др.
Опубликовано: (2017)

Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever
по: Salerno-Gonçalves, R, и др.
Опубликовано: (2022)

Cost-effectiveness analysis of typhoid conjugate vaccines in an outbreak setting: a modeling study
по: Maile T. Phillips, и др.
Опубликовано: (2023-03-01)

Induction of cell cycle and NK cell responses by live-attenuated oral vaccines against typhoid fever
по: Blohmke, CJ, и др.
Опубликовано: (2017)

Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
по: Gibani, M, и др.
Опубликовано: (2019)

Why Is Eradicating Typhoid Fever So Challenging: Implications for Vaccine and Therapeutic Design
по: Yi-An Yang, и др.
Опубликовано: (2018-07-01)

Typhoid conjugate vaccines: making vaccine history in Africa
по: James E. Meiring, и др.
Опубликовано: (2018-08-01)

Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a.
по: Thomas C Darton, и др.
Опубликовано: (2016-08-01)

A mathematical model on the transmission dynamics of typhoid fever with treatment and booster vaccination
по: Abdulai Kailan Suhuyini, и др.
Опубликовано: (2023-04-01)

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
по: McArthur, M, и др.
Опубликовано: (2015)

Modelling the impact of vaccination on transmission dynamics of Typhoid fever
по: Fatimah O. Lawal, и др.
Опубликовано: (2023-12-01)

Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease.
по: Franklin R Toapanta, и др.
Опубликовано: (2016-06-01)