HAC stability in murine cells is influenced by nuclear localization and chromatin organization

<p style="text-align:justify;"> <b>Background:</b> Human artificial chromosomes (HAC) are small functional extrachromosomal elements, which segregate correctly during each cell division. In human cells, they are mitotically stable, however when the HAC are transferred to...

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Bibliographic Details
Main Authors: Moralli, D, Chan, D, Jefferson, A, Volpi, E, Monaco, Z
Format: Journal article
Language:English
Published: BioMed Central 2009