Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides

Sialylated glycolipids, gangliosides play an essential role in the central nervous system regulating recognition and signaling in neurons. Metabolic blocks in processing and catabolism of gangliosides result in development of severe neurological disorders, gangliosidoses manifesting with neurodegene...

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Bibliographic Details
Main Authors: Pan, X, De Britto Pará De Aragão, C, Velasco-Martin, J, Priestman, D, Wu, H, Takahashi, K, Yamaguchi, K, Sturiale, L, Garozzo, D, Platt, F, Lamarche-Vane, N, Morales, C, Miyagi, T, Pshezhetsky, A
Format: Journal article
Published: Federation of American Society of Experimental Biology (FASEB) 2017