Sodium channel heterologous expression in mammalian cells and the role of the endogenous beta1-subunits.

Sodium currents in cell lines transfected with the sole alpha-subunit, or constitutively expressing sodium channels, have an inactivation that is always prevalently mono-exponential. Differently, expression of alpha-subunit in Xenopus oocytes exerts slow inactivating currents with biphasic decay, wh...

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Bibliographic Details
Main Authors: Moran, O, Conti, F, Tammaro, P
Format: Journal article
Language:English
Published: 2003