Mature, long-lived CD4+ and CD8+ T cells are generated by the thymoma in myasthenia gravis.

Antibodies to muscle acetylcholine receptors, to other muscle antigens, and to some cytokines are found in the majority of patients with thymic tumors (thymomas) and myasthenia gravis (MG). The role of the tumor in initiating autoimmunity, however, is unclear; in particular, it is not known whether...

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Bibliographic Details
Main Authors: Buckley, C, Douek, D, Newsom-Davis, J, Vincent, A, Willcox, N
Format: Journal article
Language:English
Published: 2001