The first example of a 6-C-aryl-D-glucose: Inhibition of glucokinase
The synthesis of the epimeric 6-C-phenylglucoses is reported; these are the first compounds with one of the prochiral methylene hydrogens on C-6 of a hexose being replaced by an aryl group. Both isomers inhibit glucokinase and provide further indications that 6-C-alkyl- and 6-C-aryl-carbohydrates ma...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1996
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