Hydrogen bonding phase-transfer catalysis with ionic reactants: enantioselective synthesis of γ-fluoroamines
Ammonium salts are used as phase-transfer catalysts for fluorination with alkali metal fluoride. We now demonstrate that these organic salts, specifically azetidinium triflates, are suitable substrates for enantioselective ring opening with CsF and a chiral bis-urea catalyst. This process that highl...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2020
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