Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.

OBJECTIVE: The role of constitutive nitric oxide (NO) production in the regulation of beta-adrenergic and muscarinic responses remains controversial. Conflicting data in left ventricular (LV) myocytes from eNOS knockout mice (eNOS-/-) have been ascribed to inconsistent experimental conditions (i.e....

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Bibliographic Details
Main Authors: Martin, SR, Emanuel, K, Sears, C, Zhang, Y, Casadei, B
Format: Journal article
Language:English
Published: 2006