Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.
BACKGROUND: In comparison to the classical isoforms of protein kinase C (PKC), the novel isoforms are thought to play minor or inhibitory roles in the regulation of platelet activation and thrombosis. OBJECTIVES: To measure the levels of PKCθ and PKCε and to investigate the phenotype of mice deficie...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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