Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

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BACKGROUND: In comparison to the classical isoforms of protein kinase C (PKC), the novel isoforms are thought to play minor or inhibitory roles in the regulation of platelet activation and thrombosis. OBJECTIVES: To measure the levels of PKCθ and PKCε and to investigate the phenotype of mice deficie...

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Bibliographic Details
Main Authors:	Unsworth, A, Finney, B, Navarro-Nunez, L, Severin, S, Watson, S, Pears, C
Format:	Journal article
Language:	English
Published:	2012

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