The matrix protein of rabies virus binds to RelAp43 to modulate NF-κB-dependent gene expression related to innate immunity.

The matrix (M) protein of wild isolates of rabies virus such as Tha (M-Tha) was previously shown to be able to interact with RelAp43, a protein of the NF-κB family, and to efficiently suppress NF-κB-dependent reporter gene expression, in contrast with the vaccine strain SAD. Here, we analyze the mec...

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Bibliographic Details
Main Authors: Ben Khalifa, Y, Luco, S, Besson, B, Sonthonnax, F, Archambaud, M, Grimes, J, Larrous, F, Bourhy, H
Format: Journal article
Language:English
Published: Nature Publishing Group 2016