Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.

BACKGROUND: Stress-induced hypertrophic remodeling is a critical pathogenetic process leading to heart failure. Although many signal transduction cascades are demonstrated as important regulators to facilitate the induction of cardiac hypertrophy, the signaling pathways for suppressing hypertrophic...

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Hlavní autoři: Liu, W, Zi, M, Naumann, R, Ulm, S, Jin, J, Taglieri, D, Prehar, S, Gui, J, Tsui, H, Xiao, R, Neyses, L, Solaro, R, Ke, Y, Cartwright, E, Lei, M, Wang, X
Médium: Journal article
Jazyk:English
Vydáno: 2011