Opioids depress cortical centers responsible for the volitional control of respiration.
Respiratory depression limits provision of safe opioid analgesia and is the main cause of death in drug addicts. Although opioids are known to inhibit brainstem respiratory activity, their effects on cortical areas that mediate respiration are less well understood. Here, functional magnetic resonanc...
Главные авторы: | Pattinson, K, Governo, R, MacIntosh, B, Russell, E, Corfield, DR, Tracey, I, Wise, R |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2009
|
Схожие документы
-
Opioids modulate the brain activity associated with breath holding: an functional magnetic resonance imaging study
по: Pattinson, K, и др.
Опубликовано: (2009) -
Opioids and the control of respiration.
по: Pattinson, K
Опубликовано: (2008) -
Pharmacological FMRI: measuring opioid effects on the BOLD response to hypercapnia.
по: Pattinson, K, и др.
Опубликовано: (2007) -
Neural activity related to volitional regulation of cortical excitability
по: Kathy Ruddy, и др.
Опубликовано: (2018-11-01) -
Modelling the effect of remifentanil on respiratory variability
по: Pattinson, K, и др.
Опубликовано: (2008)