The effects of hypomorphic STAT3 on lymphocyte function and intestinal immune regulation
<p>Dominant-negative mutations in signal transducer and activator of transcription 3 (STAT3) underlie the human primary immunodeficiency autosomal dominant hyper IgE syndrome (HIES). A number of aspects of this disease, including the eponymous elevated serum IgE, remain poorly understood. Addi...
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| Médium: | Diplomová práce |
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2012
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