Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK.

TRESK is a two-pore domain potassium channel. Loss of function mutations have been linked to typical migraine with aura and due to TRESK’s expression pattern and role in neuronal excitability it represents a promising therapeutic target. We developed a cell based assay using baculovirus transduced U...

詳細記述

書誌詳細
主要な著者: Wright, P, Weir, G, Cartland, J, Tickle, D, Kettleborough, C, Cader, M, Jerman, J
フォーマット: Journal article
言語:English
出版事項: 2013