Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption
Introduction Osteoclasts are responsible for the bone loss associated with rheumatoid arthritis (RA). The secreted adipokine angiopoietin-like 4 (ANGPTL4) specifically increases osteoclast-mediated bone resorption. We have investigated expression of ANGPTL4 and its regulatory transcription factor, h...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2014
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