Relationship of the K-ras/c-mos expression patterns with angiogenesis in non-small cell lung carcinomas.

BACKGROUND: Neo-angiogenesis is an acquired capability vital for a tumor to grow and metastasize. Evidence has shown that the mitogen-activated protein (MAP) kinase pathway is involved in this process. Alterations of K-ras and c-mos, two pivotal components of this pathway, have been implicated in no...

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Main Authors: Zacharatos, P, Kotsinas, A, Tsantoulis, P, Evangelou, K, Kletsas, D, Asimacopoulos, P, Doussis-Anagnostopoulou, I, Pezzella, F, Gatter, K, Papavassiliou, A, Kittas, C, Gorgoulis, V
Format: Journal article
Language:English
Published: 2001