Targeting the small GTPase superfamily through their regulatory proteins

The Ras superfamily of small GTPases are guanine nucleotide dependent switches essential for numerous cellular processes. Mutations or dysregulation of these proteins are associated with many diseases, but unsuccessful attempts to target the small GTPases directly have resulted in them being classed...

Full description

Bibliographic Details
Main Authors: Gray, J, Von Delft, F, Brennan, P
Format: Journal article
Language:English
Published: Wiley 2019