Mechanical properties of cardiac titin's N2B-region by single-molecule atomic force spectroscopy.

Titin is a giant protein responsible for passive-tension generation in muscle sarcomeres. Here, we used single-molecule AFM force spectroscopy to investigate the mechanical characteristics of a recombinant construct from the human cardiac-specific N2B-region, which harbors a 572-residue unique seque...

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Bibliographic Details
Main Authors: Leake, M, Grützner, A, Krüger, M, Linke, W
Format: Journal article
Language:English
Published: 2006