Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence

<p style="text-align:justify;"> Intimate bacterial adhesion to intestinal epithelium is a pathogenic mechanism shared by several human and animal enteric pathogens, including enteropathogenic and enterohaemorrhagic Escherichia coli and Citrobacter rodentium. The proteins directly in...

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Bibliographic Details
Main Authors: Reece, S, Simmons, C, Fitzhenry, R, Batchelor, M, Hale, C, Matthews, S, Phillips, A, Dougan, G, Frankel, G
Format: Journal article
Language:English
Published: Microbiology Society 2002