Investigation of the effects of IGF-1 receptor blockade on chemoresistance of advanced melanoma
<p>Advanced melanoma poses a major therapeutic challenge, and despite the development of recent promising therapeutic agents, resistance to treatment remains a problem. Until recently, despite low response rates, alkylating agents dacarbazine and temozolomide (TMZ) were the standard of care fo...
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Format: | Thesis |
Language: | English |
Published: |
2014
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