Investigation of the effects of IGF-1 receptor blockade on chemoresistance of advanced melanoma

<p>Advanced melanoma poses a major therapeutic challenge, and despite the development of recent promising therapeutic agents, resistance to treatment remains a problem. Until recently, despite low response rates, alkylating agents dacarbazine and temozolomide (TMZ) were the standard of care fo...

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Bibliographic Details
Main Authors: Ramcharan, R, Roger Ramcharan
Other Authors: Macaulay, V
Format: Thesis
Language:English
Published: 2014
Subjects: