The distribution and causes of meiotic recombination in the human genome.

The distribution and causes of meiotic recombination in the human genome.

Using the statistical analysis of genetic variation, we have developed a high-resolution genetic map of recombination hotspots and recombination rate variation across the human genome. This map, which has a resolution several orders of magnitude greater than previous studies, identifies over 25,000...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Myers, S, Spencer, C, Auton, A, Bottolo, L, Freeman, C, Donnelly, P, McVean, G
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2006

समान संसाधन

A fine-scale map of recombination rates and hotspots across the human genome.
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A common sequence motif associated with recombination hot spots and genome instability in humans.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2008)

A common sequence motif associated with recombination hot spots and genome instability in humans.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2008)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination.
द्वारा: Myers, S, और अन्य
प्रकाशित: (2010)

Estimating recombination rates from genetic variation in humans.
द्वारा: Auton, A, और अन्य
प्रकाशित: (2012)

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
द्वारा: Myers, Simon, और अन्य
प्रकाशित: (2010)

Recombination rate estimation in the presence of hotspots.
द्वारा: Auton, A, और अन्य
प्रकाशित: (2007)

Estimating meiotic gene conversion rates from population genetic data.
द्वारा: Gay, J, और अन्य
प्रकाशित: (2007)

The influence of recombination on human genetic diversity.
द्वारा: Spencer, C, और अन्य
प्रकाशित: (2006)

The influence of recombination on human genetic diversity.
द्वारा: Spencer, C, और अन्य
प्रकाशित: (2006)

Recombination Rates, their local variation and the estimated number of hotspots in the human genome.
द्वारा: Stumpf, M, और अन्य
प्रकाशित: (2003)

Scanning the human genome for signals of selection.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2006)

What drives recombination hotspots to repeat DNA in humans?
द्वारा: McVean, G
प्रकाशित: (2010)

The fine-scale structure of recombination rate variation in the human genome.
द्वारा: Mcvean, G, और अन्य
प्रकाशित: (2004)

Genome-wide control of the distribution of meiotic recombination.
द्वारा: Corinne Grey, और अन्य
प्रकाशित: (2009-02-01)

Reprogramming meiotic recombination in the mouse
द्वारा: Davies, B, और अन्य
प्रकाशित: (2014)

Linkage Disequilibrium, Recombination and Selection
द्वारा: McVean, G
प्रकाशित: (2008)

Refined genetic maps reveal sexual dimorphism in human meiotic recombination at multiple scales
द्वारा: Claude Bhérer, और अन्य
प्रकाशित: (2017-04-01)

A new multipoint method for genome-wide association studies by imputation of genotypes.
द्वारा: Marchini, J, और अन्य
प्रकाशित: (2007)

Meiotic recombination in human oocytes.
द्वारा: Edith Y Cheng, और अन्य
प्रकाशित: (2009-09-01)

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm
द्वारा: Hinch, A, और अन्य
प्रकाशित: (2019)

Estimating diversifying selection and functional constraint in the presence of recombination.
द्वारा: Wilson, D, और अन्य
प्रकाशित: (2006)

Estimating recombination rates from population-genetic data.
द्वारा: Stumpf, M, और अन्य
प्रकाशित: (2003)

Recombination and population structure in Salmonella enterica.
द्वारा: Didelot, X, और अन्य
प्रकाशित: (2011)

Perspectives on human genetic variation from the HapMap Project.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2005)

Perspectives on human genetic variation from the HapMap project
द्वारा: McVean, G, और अन्य
प्रकाशित: (2005)

Genome-Wide Association Study of Meiotic Recombination Phenotypes
द्वारा: Ferdouse Begum, और अन्य
प्रकाशित: (2016-12-01)

Human genome sequence variation and the influence of gene history, mutation and recombination.
द्वारा: Reich, D, और अन्य
प्रकाशित: (2002)

Genetic analysis of variation in human meiotic recombination.
द्वारा: Reshmi Chowdhury, और अन्य
प्रकाशित: (2009-09-01)

A model-based approach to capture genetic variation for future association studies.
द्वारा: Eyheramendy, S, और अन्य
प्रकाशित: (2007)

A coalescent-based method for detecting and estimating recombination from gene sequences.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2002)

PRDM9 marks the spot.
द्वारा: McVean, G, और अन्य
प्रकाशित: (2010)

Integration of genomic and epigenomic features to predict meiotic recombination hotspots in human and mouse
द्वारा: Przytycka, Teresa M., और अन्य
प्रकाशित: (2013)

Mapping of meiotic recombination in human preimplantation blastocysts
द्वारा: Yuanlin Ma, और अन्य
प्रकाशित: (2023-02-01)

Recombination, meiotic expression and human codon usage
द्वारा: Fanny Pouyet, और अन्य
प्रकाशित: (2017-08-01)

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
द्वारा: Wells, D, और अन्य
प्रकाशित: (2020)

A statistical method for predicting classical HLA alleles from SNP data.
द्वारा: Leslie, S, और अन्य
प्रकाशित: (2008)

An integrated map of genetic variation from 1,092 human genomes.
द्वारा: Abecasis, G, और अन्य
प्रकाशित: (2012)

Reduced meiotic recombination in rhesus macaques and the origin of the human recombination landscape.
द्वारा: Cheng Xue, और अन्य
प्रकाशित: (2020-01-01)

Disruption of CHTF18 causes defective meiotic recombination in male mice.
द्वारा: Karen M Berkowitz, और अन्य
प्रकाशित: (2012-01-01)