Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart.

Thyroid hormones can modify cardiac metabolism via multiple molecular mechanisms, yet their integrated effect on overall substrate metabolism is poorly understood. Here we determined the effect of hyperthyroidism on substrate metabolism in the isolated, perfused, contracting rat heart. Male Wistar r...

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Bibliographic Details
Main Authors: Heather, L, Cole, M, Atherton, H, Coumans, W, Evans, R, Tyler, D, Glatz, J, Luiken, J, Clarke, K
Format: Journal article
Language:English
Published: 2010