Identification of distant homologues of fibroblast growth factors suggests a common ancestor for all beta-trefoil proteins.
Determination of the structures of fibroblast growth factors and interleukin-1s has previously revealed that they both adopt a beta-trefoil fold, similar to those found in Kunitz soybean trypsin inhibitors, ricin-like toxins, plant agglutinins and hisactophilin. These families possess distinct funct...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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