Identification of distant homologues of fibroblast growth factors suggests a common ancestor for all beta-trefoil proteins.

Determination of the structures of fibroblast growth factors and interleukin-1s has previously revealed that they both adopt a beta-trefoil fold, similar to those found in Kunitz soybean trypsin inhibitors, ricin-like toxins, plant agglutinins and hisactophilin. These families possess distinct funct...

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Bibliographic Details
Main Authors: Ponting, C, Russell, R
Format: Journal article
Language:English
Published: 2000