Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT.

OBJECTIVE: ADOPT (A Diabetes Outcome Progression Trial) demonstrated that initial monotherapy with rosiglitazone provided superior durability of glycemic control compared with metformin and glyburide in patients with recently diagnosed type 2 diabetes. Herein, we examine measures of β-cell function...

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Bibliographic Details
Main Authors: Kahn, SE, Lachin, J, Zinman, B, Haffner, S, Aftring, R, Paul, G, Kravitz, BG, Herman, W, Viberti, G, Holman, R
Format: Journal article
Language:English
Published: 2011