Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells.

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells.

OBJECTIVE: The binding of FasL (CD95L) to its receptor, Fas (CD95), induces apoptosis. Studies have shown that in patients with rheumatoid arthritis (RA), T lymphocytes are resistant to FasL-induced apoptosis in vivo but are susceptible to FasL-induced apoptosis in vitro. Dysfunction in this mechan...

书目详细资料
Main Authors:	Tarr, J, Winyard, P, Ryan, B, Harries, L, Haigh, R, Viner, N, Eggleton, P
格式:	Journal article
语言:	English
出版:	2010

相似书籍

Fas/FasL promoter gene polymorphism in patients with rheumatoid arthritis
由: A. Berdeli, et al.
出版: (2012-12-01)

The Fas/FasL System in Reproduction: Survival and Apoptosis
由: Gil Mor, et al.
出版: (2002-01-01)

A mechanism of release of calreticulin from cells during apoptosis.
由: Tarr, J, et al.
出版: (2010)

Alteration of Regulation of Fas/FasL Mediated Apoptosis in Gastric Cancer
由: Reggie García Robles, et al.
出版: (2009-04-01)

Leucemia mielóide crônica e o sistema Fas-FasL Chronic myeloid leukemia and the Fas-FasL system
由: Ana Paula F. Bergantini, et al.
出版: (2005-06-01)

Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis
由: Wiesner Olaf, et al.
出版: (2005-04-01)

Defective apoptosis and tumorigenesis: role of p53 mutation and Fas/FasL system dysregulation
由: F Cappello, et al.
出版: (2010-01-01)

Fas/FasL expression in colorectal cancer. An immunohistochemical study.
由: Katarzyna Guzińska-Ustymowicz, et al.
出版: (2010-11-01)

Role of the Fas/FasL pathway in HIV or SIV disease
由: Salvato Maria S, et al.
出版: (2009-10-01)

Enhancing production and cytotoxic activity of polymeric soluble FasL-based chimeric proteins by concomitant expression of soluble FasL.
由: Aurore Morello, et al.
出版: (2013-01-01)

Retinoblastoma Hücrelerinin Çoğalmasında FasL Ekspresyonu: Fas Atağının Mekanizması
由: Hendrian Dwikoloso SOEBAGJO, et al.
出版: (2014-07-01)

The role of FasR/FasL system in pathogenesis of myeloprolyferative neoplasms
由: Spasovski Vesna, et al.
出版: (2010-01-01)

Fas/FasL Contributes to HSV-1 Brain Infection and Neuroinflammation
由: Malgorzata Krzyzowska, et al.
出版: (2021-08-01)

D-Cyclins Repress Apoptosis in Hematopoietic Cells by Controlling Death Receptor Fas and Its Ligand FasL
由: Choi, Yoon Jong, et al.
出版: (2017)

The Role of Fas-FasL Signaling Pathway in Induction of Apoptosis in Patients with Sulfur Mustard-Induced Chronic Bronchiolitis
由: Gila Pirzad, et al.
出版: (2010-01-01)

Human FasL gene is a target of β-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions.
由: Jianming Wu, et al.
出版: (2011-01-01)

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus
由: Fabien B Vincent, et al.
出版: (2020-10-01)

Expression of FasL in Proliferation of Retinoblastoma Cells: A Mechanism Fas Counterattack
由: Hendrian Dwikoloso Soebagjo, et al.
出版: (2014-08-01)

FasL Modulates Expression of Mmp2 in Osteoblasts
由: Eva Svandova, et al.
出版: (2018-09-01)

Fas/FasL-Mediated Apoptosis and Inflammation Contribute to Recovery from HSV-2-Mediated Spinal Cord Infection
由: Malgorzata Krzyzowska, et al.
出版: (2024-08-01)

Investigation of the Relation Between FAS, FASLG Polymorphisms and Serum Fas, FasL Levels in Patients with Psoriasis
由: Duran Gülay Gülbol, et al.
出版: (2018-07-01)

Fas/FasL 在复发性自然流产患者中的表达
由: 刘玉昆
出版: (2004-01-01)

HSV-2 regulates monocyte inflammatory response via the Fas/FasL pathway.
由: Malgorzata Krzyzowska, et al.
出版: (2013-01-01)

Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field.
由: Lukasz Szymanski, et al.
出版: (2018-01-01)

Expression and distribution of S-100, CD83 and apoptosis-related proteins (Fas, FasL and Bcl-2) in tissues of thyroid carcinoma
由: W Xu, et al.
出版: (2009-08-01)

18β-Glycyrrhetinic acid inhibits the apoptosis of cells infected with rotavirus SA11 via the Fas/FasL pathway
由: Xiaoyan Wang, et al.
出版: (2021-01-01)

Defective fasL reveals immunregulation after costimulation blockade.
由: Cobbold, S
出版: (2001)

FasL Is Required for Osseous Healing in Extraction Sockets in Mice
由: Karol Alí Apaza Alccayhuaman, et al.
出版: (2021-05-01)

Correlation between Fas and FasL proteins expression in normal gastric mucosa and gastric cancer
由: Jolanta Czyżewska, et al.
出版: (2011-04-01)

Fas/FasL Signaling Regulates CD8 Expression During Exposure to Self-Antigens
由: Giovanna Flores-Mendoza, et al.
出版: (2021-03-01)

90 Potentiation of T-cell mediated tumor killing via modulation of the fas/fasL pathway
由: Norah Sadek, et al.
出版: (2020-11-01)

Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis.
由: Gabriella Marfè, et al.
出版: (2011-01-01)

A Mathematical Model of Receptor-Mediated Apoptosis: Dying to Know Why FasL is a Trimer
由: Ronald Lai, et al.
出版: (2004-06-01)

Platelets Induce Cell Apoptosis of Cardiac Cells via FasL after Acute Myocardial Infarction
由: Kim J. Krott, et al.
出版: (2024-05-01)

LiCl induces TNF-α and FasL production, thereby stimulating apoptosis in cancer cells
由: Thiele Wilko, et al.
出版: (2011-05-01)

The In Situ Hybridization Expression of Fas and Fas Ligand (FasL) in Trophoblastic tissue of Aborted Women Compared with Normal Pregnancy.
由: Amal H. Salman, et al.
出版: (2009-07-01)

FasL induces expression of Mmp13 and Osterix in bone cells
由: Adéla Kratochvílová, et al.
出版: (2021-04-01)

Reverse signaling by FasL inhibits primary human T cell activation
由: Janssen O, et al.
出版: (2009-02-01)

Statement of Retraction: 18β-Glycyrrhetinic acid inhibits the apoptosis of cells infected with rotavirus SA11 via the Fas/FasL pathway
出版: (2022-12-01)

CpG oligonucleotides suppress HepG2 cells-induced Jurkat cell apoptosis <it>via </it>the Fas-FasL-mediated pathway
由: Li Jing, et al.
出版: (2011-05-01)