Phasevarions mediate random switching of gene expression in pathogenic Neisseria

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, the random switching of the modA gene controls expression of a phase-variable reg...

Full description

Bibliographic Details
Main Authors: Srikhanta, Y, Dowideit, S, Edwards, J, Falsetta, M, Wu, H, Harrison, O, Fox, K, Seib, K, Maguire, T, Wang, A, Maiden, M, Grimmond, S, Apicella, M, Jennings, M
Format: Journal article
Language:English
Published: Public Library of Science 2009