The GATAD2B-NuRD complex drives DNA:RNA hybrid-dependent chromatin boundary formation upon DNA damage

Double-strand breaks (DSBs) are the most lethal form of DNA damage. Transcriptional activity at DSBs, as well as transcriptional repression around DSBs, are both required for efficient DNA repair. The chromatin landscape defines and coordinates these two opposing events. However, how the open and co...

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Autori principali: Liu, Z, Ajit, K, Wu, Y, Zhu, W, Gullerova, M
Natura: Journal article
Lingua:English
Pubblicazione: EMBO Press 2024