SULFATION PATHWAYS: Steroid sulphatase inhibition via aryl sulphamates: clinical progress, mechanism and future prospects

SULFATION PATHWAYS: Steroid sulphatase inhibition via aryl sulphamates: clinical progress, mechanism and future prospects

Steroid sulphatase is an emerging drug target for the endocrine therapy of hormone-dependent diseases, catalysing oestrogen sulphate hydrolysis to oestrogen. Drug discovery, developing the core aryl O-sulphamate pharmacophore, has led to steroidal and non-steroidal drugs entering numerous clinical t...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteur:	Potter, B
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	BioScientifica 2018

Gelijkaardige items

SULFATION PATHWAYS: Steroid sulfatase inhibition by aryl sulfamates: clinical progress, mechanism and future prospects
door: Potter, B
Gepubliceerd in: (2018)

Steroid Sulphatase and Its Inhibitors: Past, Present, and Future
door: Paul A. Foster
Gepubliceerd in: (2021-05-01)

New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives
door: Olga Ciupak, et al.
Gepubliceerd in: (2021-01-01)

Placental steroid sulphatase deficiency: an approach to antenatal care and delivery
door: Frieda-Elsje Dreyer, et al.
Gepubliceerd in: (2018-11-01)

Recent progress in the development of steroid sulphatase inhibitors – examples of the novel and most promising compounds from the last decade
door: Mateusz Daśko, et al.
Gepubliceerd in: (2020-01-01)

Identification of oestrone sulphatase inhibitors in breast cyst fluid
door: Lai, Leslie Charles, et al.
Gepubliceerd in: (2002)

Effect of NaCl on the properties of sulphamic acid single crystals
door: J. Arumugam, et al.
Gepubliceerd in: (2019-07-01)

Investigations on Growth, Optical and Thermal Properties of Sulphamic Acid Single Crystals
door: D. Jaishree, et al.
Gepubliceerd in: (2014-01-01)

Effect of Breast Cyst Fluid on Oestrone Sulphatase Activity in Breast Cancer Celllines
door: El-Sadig, Rasha El-Hag
Gepubliceerd in: (2000)

Effect of Aquo-glycolic Media and Added Anions on the Anodization of Zircaloy-4 in Sulphamic Acid
door: Viplav Duth Shukla, et al.
Gepubliceerd in: (2011-01-01)

Identification of oestrone sulphatase inhibitors in breast cyst fluid: a new treatment for breast cancer
door: Lai, L. C.
Gepubliceerd in: (1999)

Growth, characterization, and anti-bacterial activity of l-methionine supplemented with sulphamic acid single crystals
door: Vithel Friedelin R. S., et al.
Gepubliceerd in: (2024-02-01)

Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations
door: Giuseppina De Simone, et al.
Gepubliceerd in: (2017-01-01)

Radioiodination of Aryl-Alkyl Cyclic Sulfates
door: Mikhail I. Papisov, et al.
Gepubliceerd in: (2012-11-01)

2-Methoxyestradiol-bis-sulphamate refrains from inducing apoptosis and autophagy in a non-tumorigenic breast cell line
door: Visagie Michelle H, et al.
Gepubliceerd in: (2012-08-01)

Microwave-assisted solvent-free one pot synthesis of isobenzofuran-1(3H)-ones using sulphamic acid catalyst
door: Samruddhi S. Zambre, et al.
Gepubliceerd in: (2016-11-01)

Steroid Sulfation in Neurodegenerative Diseases
door: Jana Vitku, et al.
Gepubliceerd in: (2022-02-01)

<it>In vitro </it>effects of 2-methoxyestradiol-bis-sulphamate on reactive oxygen species and possible apoptosis induction in a breast adenocarcinoma cell line
door: Visagie Michelle H, et al.
Gepubliceerd in: (2011-12-01)

Aryl Hydrocarbon Receptor Inhibition Restores Indoxyl Sulfate-Mediated Endothelial Dysfunction in Rat Aortic Rings
door: Cindy Nguyen, et al.
Gepubliceerd in: (2022-01-01)

Steroid Sulfatase Inhibition: From Concept to Clinic and Beyond
door: Barry V L Potter
Gepubliceerd in: (2019-08-01)

Sulfated and Sulfur-Containing Steroids and Their Pharmacological Profile
door: Tatyana A. Pounina, et al.
Gepubliceerd in: (2021-04-01)

Multiplexing Iduronate-2-Sulphatase (MPS-II) into a 7-Plex Lysosomal Storage Disorder MS/MS Assay Using Cold-Induced Phase Separation
door: Elya Courtney, et al.
Gepubliceerd in: (2023-06-01)

Inhibition of Human Osteoclast Differentiation by Kynurenine through the Aryl-Hydrocarbon Receptor Pathway
door: So-Yeon Kim, et al.
Gepubliceerd in: (2021-12-01)

MECHANISMS OF OSTEOBLAST INHIBITION BY STEROIDS
door: Hulley, P
Gepubliceerd in: (2004)

Assembly of (hetero)aryl sulfilimines via copper-catalyzed enantioselective S-arylation of sulfenamides with (hetero)aryl Iodides
door: Mingchuang He, et al.
Gepubliceerd in: (2025-03-01)

Role of Chondroitin Sulfate Proteoglycan 5 in Steroid-Induced Cataract
door: Woong-Sun Yoo, et al.
Gepubliceerd in: (2023-06-01)

Pregnenolone Sulfate: From Steroid Metabolite to TRP Channel Ligand
door: Christian Harteneck
Gepubliceerd in: (2013-09-01)

Dual processing of sulfated steroids in the olfactory system of an anuran amphibian
door: Alfredo eSansone, et al.
Gepubliceerd in: (2015-09-01)

Generation of Aryl Radicals from Aryl Hydrazines via Catalytic Iodine in Air: Arylation of Substituted 1,4-Naphthoquinones
door: Saibal Sar, et al.
Gepubliceerd in: (2020-02-01)

Empowering nanophotonic applications via artificial intelligence: pathways, progress, and prospects
door: Chen Wei, et al.
Gepubliceerd in: (2025-02-01)

Synthesis of 2-aryl-benzothiazoles via Ni-catalyzed coupling of benzothiazoles and aryl sulfamates
door: Yu Xiaofeng, et al.
Gepubliceerd in: (2020-02-01)

Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones.
door: Jens Neunzig, et al.
Gepubliceerd in: (2014-01-01)

Higher steroid sulfation is linked to successful weight loss in obese children
door: Thomas Reinehr, et al.
Gepubliceerd in: (2018-10-01)

High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency[S]
door: Alberto Sánchez-Guijo, et al.
Gepubliceerd in: (2015-02-01)

Rutaecarpine Inhibits U87 Glioblastoma Cell Migration by Activating the Aryl Hydrocarbon Receptor Signaling Pathway
door: Yiyun Liu, et al.
Gepubliceerd in: (2021-12-01)

Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
door: Jonathan Latham, et al.
Gepubliceerd in: (2016-06-01)

Isoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway
door: Xingyu Lv, et al.
Gepubliceerd in: (2023-12-01)

Chrysophanol Inhibits the Progression of Diabetic Nephropathy via Inactivation of TGF-β Pathway
door: Guo C, et al.
Gepubliceerd in: (2020-11-01)

Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression
door: Claudia Rejano-Gordillo, et al.
Gepubliceerd in: (2022-04-01)

1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression
door: Luiz Henrique Gomes Matheus, et al.
Gepubliceerd in: (2020-09-01)