Structural diversity in integrin/talin interactions.
The adhesion of integrins to the extracellular matrix is regulated by binding of the cytoskeletal protein talin to the cytoplasmic tail of the β-integrin subunit. Structural studies of this interaction have hitherto largely focused on the β3-integrin, one member of the large and diverse integrin fam...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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