Structural diversity in integrin/talin interactions.

The adhesion of integrins to the extracellular matrix is regulated by binding of the cytoskeletal protein talin to the cytoplasmic tail of the β-integrin subunit. Structural studies of this interaction have hitherto largely focused on the β3-integrin, one member of the large and diverse integrin fam...

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Bibliographic Details
Main Authors: Anthis, N, Wegener, K, Critchley, DR, Campbell, I
Format: Journal article
Language:English
Published: 2010