Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung in vivo. Since targeting of the human lung will depend upon the availability and distribution of r...

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Détails bibliographiques
Auteurs principaux: Munday, RJ, Coradin, T, Nimmo, R, Lad, Y, Hyde, SC, Mitrophanos, K, Gill, DR
Format: Journal article
Langue:English
Publié: Elsevier 2022