Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung in vivo. Since targeting of the human lung will depend upon the availability and distribution of r...

Full description

Bibliographic Details
Main Authors: Munday, RJ, Coradin, T, Nimmo, R, Lad, Y, Hyde, SC, Mitrophanos, K, Gill, DR
Format: Journal article
Language:English
Published: Elsevier 2022