The ins and outs of secretion from pancreatic beta-cells: control of single-vesicle exo- and endocytosis.

Exocytosis of insulin-containing secretory vesicles in pancreatic beta-cells is crucial to maintenance of plasma glucose levels. They fuse with the plasma membrane in a regulated manner to release their contents and are subsequently recaptured either intact or through conventional clathrin-mediated...

Full description

Bibliographic Details
Main Authors: MacDonald, P, Rorsman, P
Format: Journal article
Language:English
Published: 2007