The ins and outs of secretion from pancreatic beta-cells: control of single-vesicle exo- and endocytosis.
Exocytosis of insulin-containing secretory vesicles in pancreatic beta-cells is crucial to maintenance of plasma glucose levels. They fuse with the plasma membrane in a regulated manner to release their contents and are subsequently recaptured either intact or through conventional clathrin-mediated...
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Bibliographic Details
| Main Authors: |
MacDonald, P,
Rorsman, P |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2007
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