Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients

Plasmablasts are a highly differentiated, antibody secreting B cell subset whose prevalence correlates with disease activity in Multiple Sclerosis (MS). For most patients experiencing partial transverse myelitis (PTM), plasmablasts are elevated in the blood at the first clinical presentation of dise...

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Bibliographic Details
Main Authors: Rivas, JR, Ireland, SJ, Chkheidze, R, Rounds, WH, Lim, J, Johnson, J, Ramirez, DMO, Ligocki, AJ, Chen, D, Guzman, AA, Woodhall, M, Wilson, PC, Meffre, E, White, C, Greenberg, BM, Waters, P, Cowell, LG, Stowe, AM, Monson, NL
Format: Journal article
Language:English
Published: Springer 2016