Identification of a lipopolysaccharide alpha-2,3-sialyltransferase from Haemophilus influenzae.

We have identified a gene for the addition of N-acetylneuraminic acid (Neu5Ac) in an alpha-2,3-linkage to a lactosyl acceptor moiety of the lipopolysaccharide (LPS) of the human pathogen Haemophilus influenzae. The gene is one that was identified previously as a phase-variable gene known as lic3A. E...

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Bibliographic Details
Main Authors: Hood, D, Cox, A, Gilbert, M, Makepeace, K, Walsh, S, Deadman, M, Cody, A, Martin, A, Månsson, M, Schweda, E, Brisson, JR, Richards, J, Moxon, E, Wakarchuk, W
Format: Journal article
Language:English
Published: 2001