Identification of a novel role for PARPs in replication stress recovery
The post-translational modification of proteins by ADP-ribosylation, catalysed by poly(ADP-ribose) polymerases (PARPs), forms a cornerstone of the human DNA damage response. Through the covalent attachment of ADP-ribose moieties to substrate proteins, PARPs coordinate the recruitment of repair facto...
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| Format: | Abschlussarbeit |
| Sprache: | English |
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2022
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