Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness.

Integrin-ligand interactions between germinal center (GC) B cells and Ag-presenting follicular dendritic cells (FDCs) have been suggested to play central roles during GC responses, but their in vivo requirement has not been directly tested. In this study, we show that, whereas integrins αLβ2 and α4β...

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Bibliographic Details
Main Authors: Wang, X, Rodda, L, Bannard, O, Cyster, J
Format: Journal article
Language:English
Published: 2014