Indolyne and aryne distortions and nucleophilic regioselectivites.

Indolyne and aryne distortions and nucleophilic regioselectivites.

Density functional theory computations reproduce the surprisingly high regioselectivities in nucleophilic additions and cycloadditions to 4,5-indolynes and the low regioselectivities in the reactions of 5,6-indolynes. Transition-state distortion energies control the regioselectivities, activating th...

Полное описание

Библиографические подробности
Главные авторы:	Cheong, P, Paton, R, Bronner, S, Im, G, Garg, N, Houk, K
Формат:	Journal article
Язык:	English
Опубликовано:	2010

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