High resolution melting for mutation scanning of TP53exons 5–8

<p style="text-align:justify;"> <b>Background:</b> p53 is commonly inactivated by mutations in the DNA-binding domain in a wide range of cancers. As mutant p53 often influences response to therapy, effective and rapid methods to scan for mutations in TP53 are likely to b...

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Bibliographic Details
Main Authors: Krypuy, M, Ahmed, A, Etemadmoghadam, D, Hyland, S, Defazio, A, Fox, S, Brenton, J, Bowtell, D, Dobrovic, A
Format: Journal article
Language:English
Published: BioMed Central 2007