High resolution melting for mutation scanning of TP53exons 5–8
<p style="text-align:justify;"> <b>Background:</b> p53 is commonly inactivated by mutations in the DNA-binding domain in a wide range of cancers. As mutant p53 often influences response to therapy, effective and rapid methods to scan for mutations in TP53 are likely to b...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2007
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