T-cell-depleted allogeneic bone marrow transplantation for acute leukaemia using Campath-1 antibodies and post-transplant administration of donor's peripheral blood lymphocytes for prevention of relapse.

One hundred and forty-six patients with acute leukaemia (81 with ANLL and 65 with ALL) received allogeneic bone marrow transplantation from their fully matched siblings. 121 patients underwent T-cell depletion (TCD) using Campath 1 monoclonal rat anti-human lymphocyte (CDw52) antibodies; 67 with Cam...

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Bibliographic Details
Main Authors: Naparstek, E, Or, R, Nagler, A, Cividalli, G, Engelhard, D, Aker, M, Gimon, Z, Manny, N, Sacks, T, Tochner, Z
Format: Journal article
Language:English
Published: 1995