CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts.

Human NK cells are divided into CD56(bright)CD16(-) cells and CD56(dim)CD16(+) cells. We tested the hypothesis that CD56(bright) NK cells can differentiate into CD56(dim) cells by prospectively isolating and culturing each NK subset in vitro and in vivo. Our results show that CD56(bright) cells can...

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Bibliographic Details
Main Authors: Chan, A, Hong, D, Atzberger, A, Kollnberger, S, Filer, A, Buckley, C, McMichael, A, Enver, T, Bowness, P
Format: Journal article
Language:English
Published: 2007