Investigating strategies to modify PARP14 function through macrodomain inhibition
<p>Macrodomains are conserved protein interaction modules that are present in all domains of life and mediate recognition of sequence motifs harbouring adenosine diphosphate ribose (ADPR) modifications. In addition, some of them are able to control the turnover of ADPR signalling through their...
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| Format: | Thesis |
| Language: | English |
| Published: |
2017
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