Information for genetic management of mtDNA disease: Sampling pathogenic mtDNA mutants in the human germline and in placenta
Background: Families with a child who died of severe, maternally inherited mitochondrial DNA (mtDNA) disease need information on recurrence risk. Estimating this risk is difficult because of (a) heteroplasmyd - the coexistence of mutant and normal mtDNA in the same persond - and (b) the so-called mi...
| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
2010
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